Treatment Information

Back

Colon Cancer treatment details. Chemotherapy.

University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Survival: monthsCountry:United States
Toxiciy Grade:4City/State/Province:Pittsburgh, PA
Treatments:ChemotherapyHospital:University of Pittsburgh School of Medicine
Drugs:Journal:Link
Date:Mar 2006

Description:

Patients: This Phase II study involved 14 patients (11 men, 3 women, median age 70) with advanced colorectal cancer. All patients had received surgery or chemotherapy before the study.

Treatment: Treatment consisted of one chemotherapeutic agent: rubitecan.

Toxicity: Grade 3-4 toxicities included anemia, diarrhea and elevated bilirubin.

Results: The median overall survival was 10.1 months, and no objective responses were observed. The authors concluded, "Administration of rubitecan was well-tolerated, but this schedule does not appear to have clinical activity in patients with advanced previously treated colorectal cancer."

Correspondence: Ramesh K. Ramanathan




Back