Treatment Information

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Lung Cancer treatment details. Chemotherapy.

Christie Hospital, Manchester, United Kingdom.

Survival: monthsCountry:United Kingdom
Toxiciy Grade:5City/State/Province:Manchester
Treatments:ChemotherapyHospital:Christie Hospital
Drugs:Journal:Link
Date:Jul 2006

Description:

Patients: This Phase III trial involved a total of 433 patients with advanced non-small-cell lung cancer. There were 295 men and 138 women. The median age was 63. Patients were divided into two groups. Group A comprised of 216 patients had Group B of 217 patients.

Treatment: The treatment for patients in Group A consisted of two chemotherapy drugs (docetaxel and carboplatin). The treatment for patients in Group B consisted of two chemotherapy regimens (mitomycin C and ifosfamide and cisplatin, or mitomycin C and vinblastine and cisplatin).

Toxicity: There were 69 early deaths (survival of less than 112 days) the majority attributable to cancer. There were six toxic deaths due to sepsis (several in both groups).

Results: The median overall survival for patients in Group A was 9.5 months. For Group B it was 8.7 months.

Correspondance: Dr. P. Lorigan




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