Treatment Information

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Lung Cancer treatment details. Chemotherapy.

US Oncology, Inc., Houston, Texas, United States.

Survival: monthsCountry:United States
Toxiciy Grade:4City/State/Province:Houston, Texas
Treatments:ChemotherapyHospital:US Oncology, Inc.
Drugs:Journal:Link
Date:Feb 2003

Description:

Patients: This Phase II study involved 51 patients with advanced (stage IIIB or IV) non-small cell lung cancer. The median age of the patients was 64.

Treatment: The treatment consisted of the administration of two drugs – topotecan (hycamtin) and gemcitabine (gemzar).

Toxicity: Grade 3 and 4 toxicities included neutropenia (53% of patients), anemia, thrombocytopenia, asthenia, and gastrointestinal disorders. Other toxicities included pneumonia, shortness of breath, fever, dyspnea, pulmonary toxicity, myocardial infarction, and pneumonitis.

Results: Median overall survival was 7.6 months.

Support: The study was supported by SmithKline Beecham Pharmaceuticals, Inc.




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