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Colon Cancer treatment details. Biologic therapy.

Hospital Clinico San Carlos , Madrid , Spain.

Survival: monthsCountry:Spain
Toxiciy Grade:5City/State/Province:Madrid
Treatments:Biologic therapyHospital:Hospital Clinico San Carlos
Drugs:Journal:Link
Date:Jul 2015

Description:

Patients:
This phase 2 study involved 33 frail, elderly, wild-type KRAS metastatic colorectal cancer patients. The median patient age was 81 years (range 73-89) and 66.7% were male.

Treatment:
Patients received biologic therapy with panitumumab, a monoclonal antibody specific to the EGFR protein.

Toxicities:
There were 3 reported adverse event-related deaths. Grade 3 rash, diarrhea, and fatigue were also reported.

Results:
The median overall survival was 7.1 months.

Support:
This study was supported by Amgen, makers of the study drug.

Correspondence: Dr. J. Sastre; email: [email protected]



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