Treatment Information

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Mesothelioma treatment details. Biologic therapy.

Emory University, Atlanta, GA, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:Atlanta, GA
Treatments:Biologic therapyHospital:Emory University
Drugs:Journal:Link
Date:Jan 2009

Description:

Patients:
This phase II study involved 13 previously treated advanced mesothelioma patients with a median age of 73 years; 8 were male.

Treatment:
Patients were treated with the biologic therapy agent belinostat, which is an inhibitor of a protein involved in DNA replication and cancer cell growth.

Toxicities:
There was one death due to heart attack that may have been related to treatment. Grade 4 shortness of breath and hypoxia (low oxygen levels in body) were also reported, as was grade 3 fatigue.

Results:
The median overall survival was 5 months.

Correspondence: Dr. Suresh S. Ramalingam; email: [email protected]



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