Treatment Information

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Mesothelioma treatment details. Chemotherapy, Surgery.

University Hospital Zurich, Zurich, Switzerland.

Survival: monthsCountry:Switzerland
Toxiciy Grade:5City/State/Province:Zurich
Treatments:Chemotherapy, SurgeryHospital:University Hospital Zurich
Drugs:Journal:Link
Date:Apr 2007

Description:

Patients: This study enrolled 61 patients (57 men and 4 women) with malignant pleural mesothelioma. The median age was 59 years, ranging from 44-72.

Treatment: Fifty-eight patients completed three cycles of chemotherapy with cisplatin and gemcitabine. 45 of these patients had surgery (extrapleural pneumonectomy) and radiation after finishing the chemotherapy.

Toxicity: Grade 3 and 4 toxicities included: nausea and vomiting, myalgia, dyspnea, leucopenia, and thrombocytopenia. Major postoperative complications occurred in 16 (35%)
of the patients undergoing EPP. Mortality was 2.2%

Results: The median overall survival was 19.8 months for the 61 patients. For the 45 that also underwent surgery, the median overall survival was 23 months.

Correspondence: Dr. R.A. Stahel




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