Treatment Information

Back

Brain – Glioblastoma Multiforme treatment details. Chemotherapy, Radiation, Immunotherapy.

University of Tsukuba, Tsukuba, Japan.

Survival: monthsCountry:Japan
Toxiciy Grade:4City/State/Province:Tsukuba
Treatments:Chemotherapy, Radiation, ImmunotherapyHospital:University of Tsukuba
Drugs:Journal:Link
Date:Jul 2014

Description:

Patients:
This phase 2 study involved 24 glioblastoma multiforme patients who had not received prior chemotherapy. The average patient age was 48 years and 17 were male.

Treatment:
Patients were treated with radiation therapy, chemotherapy with temozolomide, and immunotherapy with autologous formalin-fixed tumor vaccine (AFTV) for which patients received their own immune cells that had been previously removed and “trained” to attack tumor cells.

Toxicities:
The most severe toxicities were grade 4 lymphopenia and neutropenia. Grade 1 skin reactions and alopecia were also reported.

Results:
The median overall survival was 22.2 months.

Support:
This study was partially supported by Cell-Medicine, Inc.

Correspondence: Dr. Eiichi Ishikawa; email: [email protected]



Back