Treatment Information

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Breast Cancer treatment details. Chemotherapy, Biologic therapy.

St. Louis Cancer and Breast Institute, St. Louis, MO, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:St. Louis, MO
Treatments:Chemotherapy, Biologic therapyHospital:St. Louis Cancer and Breast Institute
Drugs:Journal:Link
Date:Oct 2012

Description:

Patients:
This phase 2 study involved 52 female metastatic breast cancer patients. The median patient age was 55 years.

Treatment:
Patients were treated with the chemotherapy agent gemcitabine and the biologic therapy agent bevacizumab.

Toxicities:
There was one adverse event-related death due to heart attack. Grade 4 neutropenia and leukopenia were reported. Also, 51.9% of patients reported nausea, 46.2% reported fatigue, and 13.5% reported alopecia.

Results:
The median overall survival was 21 months.

Support:
This study was supported by the pharmaceutical companies Eli Lilly and Genentech/Roche.

Correspondence: Dr. Denise A. Yardley; email: [email protected]



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