Treatment Information

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Mesothelioma treatment details. Chemotherapy, Biologic therapy.

University of Texas Southwestern Medical Center, Dallas,TX, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:Dallas,TX
Treatments:Chemotherapy, Biologic therapyHospital:University of Texas Southwestern Medical Center
Drugs:Journal:Link
Date:Sep 2012

Description:

Patients:
This phase II study involved 53 previously untreated patients with advanced malignant mesothelioma. The median patient age was 66 years and 85% were male.

Treatment:
Patients were treated with the chemotherapy agents cisplatin and pemetrexed, in addition to the biologic therapy bevacizumab.

Toxicities:
There were two treatment-related deaths reported. Grade 3 fatigue and Grade 4 pulmonary embolism were also reported.

Results:
The median overall survival was 14.8 months.

Support:
This study was supported by the pharmaceutical study Genentech, Inc.

Correspondence: Dr. Jonathan E. Dowell; email: [email protected]



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