Treatment Information

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Liver Cancer treatment details. Biologic therapy.

Herbert Irving Comprehensive Cancer Center, New York, NY, United States.

Survival: monthsCountry:United States
Toxiciy Grade:5City/State/Province:New York, NY
Treatments:Biologic therapyHospital:Herbert Irving Comprehensive Cancer Center
Drugs:Journal:Link
Date:Jun 2008

Description:

Patients:
This phase II study involved 46 patients with hepatocellular carcinoma with a median age of 58 years; 83% were male.

Treatment:
Patients were treated with the biologic therapy agent bevacizumab, a monoclonal antibody that inhibits a protein involved in supporting tumor blood supply.

Toxicities:
There was one treatment-related death due to bleeding. Grade 4 hypertension and liver toxicity.

Results:
The reported median overall survival was 12.4 months.

Support:
One of the authors was employed by the pharmaceutical company ImClone Systems, Inc.

Correspondence: Dr. Abby B. Siegel; email: [email protected]



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